Accuracy of Neck U/S in Comparison with Frozen Section in Suspicious Solitary Thyroid Nodule

Authors

  • Mohammed Shehata Zarad Department of surgery, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.
  • Boshra Ali Ali Elhoseiny Department of surgery, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt
  • Heba Anwar Shoman Department of Internal Medicine, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt
  • Amal H Ibrahim Department of Internal Medicine, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt
  • Tamer Mohamed Abd Elkader Department of Internal Medicine, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
  • Marwa Mohy Eldin Abdelrahman Ahmed Department of Internal Medicine, Faculty of Medicine, Benha University, Egypt
  • Sami Abdallah Mohamed Department of Pathology, Faculty of Medicine, Al-Azhar University, Damietta, Egypt
  • Shimaa Mohamed Mohamed Ahmed Department of Radio diagnosis, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt
  • Marwa Mostafa Fadel Sonbol Department of Radio diagnosis, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt
  • Elsayed Mohamed Abd El-Hamid Hassan Department of Radio diagnosis, Faculty of Medicine, Al-Azhar University, Damietta, Egypt

Keywords:

Ultrasound, Frozen Section, Solitary, Thyroid Nodule, Suspicious

Abstract

Background: Thyroid nodules are common, especially in women, with a rising incidence due to increased ultrasound use. Surgeons rely on ultrasound and frozen sections for diagnosing thyroid nodules. Aim: This study aimed to compare the accuracy of ultrasound and frozen sections in detecting malignant or suspicious solitary thyroid nodules and evaluate clinical pathology records. Materials and Methods: Medical records of individuals with suspicious solitary thyroid nodules at Al-Zahraa and Al-Azhar University Hospital, New Damietta, from April 2022 to April 2023 were prospectively analyzed. Nodules were categorized using the ACR TIRADS scoring system, and histological diagnoses were compared to ultrasound and frozen section findings. Sensitivity, specificity, and predictive values were assessed. Results: Among 50 participants (mean age 53.4 ± 8.0 years), anterior neck swelling (60%) was the most common symptom. Ultrasound indicated all patients had suspicious thyroid nodules. According to TIRADS, 58% were highly suspicious. Frozen sections identified malignant tumors in 70% and indeterminate nodules in 20%. Ultrasound had 89% sensitivity, while frozen sections had 67%. Specificity was 93% for ultrasound and 96.6% for frozen sections. Conclusion: Ultrasound is a reliable tool for diagnosing malignant solitary thyroid nodules in the absence of frozen sections, and it can support the diagnosis when used alongside frozen sections.

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Published

2024-12-24

Issue

Vol. 23 No. 1 (2024): Journal of Carcinogenesis Vol 23, Issue 1

Section

Articles