Younger Patients with Colorectal Cancer Presents with More Advanced Disease at Initial Presentation in Iraq

Abstract

Background: Colorectal cancer is the third most common type of cancer in oncologic pathology, and it is considered the second most common cause of death related to cancer affecting men as women in the same manner worldwide, the onset of disease in genetic CRCs is known to be about 45 years old, but sporadic CRCs are mostly patients aged 65 years or older. However, recent reports show an increasing incidence among young people. Aim of the study: To raise the index of suspicion for early colorectal cancer that develops in persons under the screening age (<50 years old). Patients and method: A retrospective case control study started from January 2019 to the end of December 2022 in the Department of General Surgery at surgical wards in Al Imamain Alkadhumain Teaching Hospital. 176 patients, newly diagnosed as a case of CRC at our center during the study period were included. Results: Male was common in young and old age (62%, and 68.3%) respectively than female and the most common tumor location was in rectum (34%), While in (≥50) is descending colon (34%), significant difference between both groups regarding the site of tumor (P><0.001) (left sided is significant). Significant difference found between both groups in the study regarding staging of tumor in the left side (p=0.005). Conclusion: The clinical suspicion for colorectal carcinoma should be kept high in young age group (><50 years) with suspected clinical features>50 years old). Patients and method: A retrospective case control study started from January 2019 to the end of December 2022 in the Department of General Surgery at surgical wards in Al Imamain Alkadhumain Teaching Hospital. 176 patients, newly diagnosed as a case of CRC at our center during the study period were included. Results: Male was common in young and old age (62%, and 68.3%) respectively than female and the most common tumor location was in rectum (34%), While in (≥50) is descending colon (34%), significant difference between both groups regarding the site of tumor (P<0.001) (left sided is significant). Significant difference found between both groups in the study regarding staging of tumor in the left side (p=0.005). Conclusion: The clinical suspicion for colorectal carcinoma should be kept high in young age group (><50 years) with suspected clinical features> <0.001) (left sided is significant). Significant difference found between both groups in the study regarding staging of tumor in the left side (p=0.005). Conclusion: The clinical suspicion for colorectal carcinoma should be kept high in young age group (<50 years) with suspected clinical features.><50 years) with suspected clinical features.