Effect of zinc oxide nanoparticles on the pancreas functions in albino mice

Authors

  • Majida Jumahh Al-Ragi Ministry of Education, Baghdad, Iraq
  • Sahar S. Karieb Department of Biology, College of Education for Pure Science (Ibn Al-Haitham), University of Baghdad, Baghdad, Iraq
  • Amira ZAÏRI Faculty of Medicine (Ibn El Gazzar) University of Sousse, Tunisia

Keywords:

Nanoparticles, zinc oxide, pancreas, Amylase, Lipase.

Abstract

The study was conducted on 40 male Swiss albino mice that were obtained from the Research and Development Authority of the Ministry of Industry and Minerals in Baghdad to determine the effect of zinc oxide nanoparticles (ZnO-Nps) on the. pancreas The animals were divided into five groups, each group containing eight mice, which were treated orally with 0.1 ml once daily of zinc oxide nanoparticles at two concentrations of 100 and 200 mg/kg for two periods of 7 and 14 days, while the control group received water and diet only. After completing the two dosage periods, the body weights were recorded, and the blood samples were collected from the treated and control animals; then the animals were sacrificed in order to study the functional, morphological and histological changes of (pancreas) that occurred as a result of treatment with zinc oxide nanoparticles.

Downloads

Published

2023-12-01

Issue

Vol. 22 No. 1 (2023): Journal of Carcinogenesis Vol 22, Issue 1

Section

Articles