Enhancing the Antibacterial Activity of Synthesized Silver Nanoparticles with Weak Static Magnetic Fields: A Comparative Study on Bacterial Growth Inhibition

Abstract

The use of silver nanoparticles as a potential solution to the problem of antimicrobial-resistant bacteria is a huge concern with antibiotic resistance, especially multidrug-resistant bacteria. Because antimicrobial-resistant bacteria endanger the security and effectiveness of contemporary medical procedures Antibiotic resistance is used to biosynthesize silver nanoparticles by Pseudomonas aeruginosa. The paper will compare the antibacterial activity of silver nanoparticles synthesized by biological by well diffusion method with and without the effect of the weak static magnetic field. The UV spectrophotometer showed the peak absorption at 421nm wavelength. Transmission electron microscopy(TEM) showed nanoparticles were homogeneous and spherical in shape with an average size of 24.5 nm, energy dispersive X-ray spectroscopy(EDS), confirm the purity of the synthesized nanoparticle Atomic force microscopy(AFM) Showed an average diameter of 56.76 nm, XRD Showed the crystallites with average size36.6nm of the synthesized nanoparticles, zeta potential was fined to be -29.30 mv and field emission scanning electron microscopy(FESEM) Was Find Between (23-24.9)nm. Where it was observed that the best inhibitory the minimum inhibitory concentration was 32 μg/ml concentration and showed the best efficacy against resistant strains of Gram-positive and negative bacteria against multidrug-resistant bacteria, and Study Cytoxocity Assay A549 on the carcinoma cell line.